Judit Tulla-Puche

Title: Innovations of Judit Tulla-Puche

Introduction

Judit Tulla-Puche is a notable inventor based in Palafrugell, Spain. She has made significant contributions to the field of peptide synthesis and antitumoral compounds. With a total of 2 patents, her work has garnered attention in the scientific community.

Latest Patents

One of her latest patents is focused on diketopiperazine forming dipeptidyl linker. This invention relates to a method for homogeneous solution phase peptide synthesis (HSPPS) of a N-terminal peptide fragment PEP-N and a C-terminal peptide fragment C-PEP. The C-PEP carries a specific diketopiperazine (DKP) that includes a C-terminal protecting group, which contains a handle group HG. This handle group is connected to the C-terminus of the peptide fragment, allowing for selective cleavage from the peptide. The use of this DKP and HG can streamline certain process steps in convergent peptide synthesis, combining HSPPS and solid phase peptide synthesis (SPPS). Additionally, she has developed antitumoral compounds of Formula I, which are useful as antitumor agents, including their pharmaceutically acceptable salts, derivatives, tautomers, prodrugs, or stereoisomers.

Career Highlights

Throughout her career, Judit has worked with prominent companies such as Pharma Mar and Lonza. Her expertise in peptide synthesis and drug development has positioned her as a valuable asset in the pharmaceutical industry.

Collaborations

Judit has collaborated with notable professionals in her field, including Fernando Albericio and Eleonora Marcucci. These collaborations have further enhanced her research and contributions to innovative solutions in medicine.

Conclusion

Judit Tulla-Puche's work in peptide synthesis and antitumoral compounds showcases her innovative spirit and dedication to advancing medical science. Her patents reflect her commitment to developing effective solutions for complex challenges in healthcare.