Company Filing History:
Years Active: 2018-2022
Title: Joyce Lichi Yang: Innovator in Genome Engineering
Introduction
Joyce Lichi Yang is a prominent inventor based in Cambridge, MA (US). She has made significant contributions to the field of genome engineering, holding 3 patents that focus on innovative methods for altering DNA in cells.
Latest Patents
Her latest patents include groundbreaking methods for genome engineering. One patent describes techniques for altering target DNA in genetically modified cells that express a Cas9 enzyme. This method involves forming a co-localization complex with a guide RNA that is complementary to the target DNA, allowing for site-specific cleavage of the DNA. The process includes introducing a foreign nucleic acid encoding a donor sequence into the cell, guiding the Cas9 enzyme to the target DNA, and ultimately inserting the donor sequence to produce altered DNA.
Another patent focuses on the use of Cas9 in genome engineering of stem cells. This method similarly involves introducing a guide RNA and a donor nucleic acid sequence into the stem cell. The guide RNA directs the Cas9 enzyme to the target DNA, leading to the cleavage of the target DNA and the insertion of the donor nucleic acid, resulting in altered DNA within the stem cell.
Career Highlights
Joyce Lichi Yang is affiliated with Harvard College, where she continues her research and development in genome engineering. Her work has positioned her as a leading figure in the field, contributing to advancements that have the potential to impact various areas of biotechnology and medicine.
Collaborations
She collaborates with notable scientists such as George M. Church and Luhan Yang, further enhancing her research through shared expertise and innovative ideas.
Conclusion
Joyce Lichi Yang's contributions to genome engineering exemplify her role as a pioneering inventor. Her patents reflect her commitment to advancing scientific knowledge and technology in the field of genetics.