Company Filing History:
Years Active: 2000-2002
Title: An Overview of Inventor Joy L. Silen
Introduction
Joy L. Silen, a prominent inventor based in Belmont, CA, has made significant contributions in the field of biochemistry, specifically through her innovative work involving enzyme technology. With a total of three patents to her name, she has focused her efforts on enhancing the capabilities of immunoassays using mutant enzymes.
Latest Patents
Her latest patents revolve around the development of homogeneous immunoassays utilizing mutant glucose-6-phosphate dehydrogenases (G6PDH) as labels. This groundbreaking invention relates to methods for immunoassaying analytes by employing conjugates of analytes or analyte analogs with mutant NAD-dependent G6PDH enzymes.
Silen's patents detail the construction of several mutations in precursor G6PDH enzymes, including the deletion or substitution of one or more lysine residues and the introduction of cysteine residues. Furthermore, these inventions encompass specific binding pairs, kits for performing the methods, cell lines producing the subject enzymes, as well as DNA sequences and vectors designed for host cell production of these enzymes.
Career Highlights
Throughout her career, Joy L. Silen has worked at reputable organizations, including Behringwerke Aktiengesellschaft, where she collaborated on various projects to advance biochemical research and applications. Her innovative approach to enzyme technology has positioned her as a noteworthy figure in her field, contributing to significant advancements in the accuracy and efficiency of immunoassays.
Collaborations
In her professional journey, Silen has collaborated with distinguished colleagues, including Edward Benjamin Jakobovits and Mark J. Levy. These partnerships have played a vital role in fostering innovation and driving her research forward, resulting in the successful development of her patented technologies.
Conclusion
Joy L. Silen's dedication to innovation in the realm of biochemistry through her patented inventions showcases the impact of her work on analyzing biological substances. Her contributions, particularly in the field of immunoassays and enzyme functionality, continue to influence research and development, reflecting the importance of her role as an inventor.
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