Company Filing History:
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Years Active: 2019-2024
Title: The Innovative Contributions of Joshua Gustafson
Introduction
Joshua Gustafson is a notable inventor based in Seattle, WA (US). He has made significant contributions to the field of biotechnology, particularly in the development of advanced therapies for cancer treatment. With a total of 2 patents, Gustafson's work is paving the way for innovative solutions in medical science.
Latest Patents
Gustafson's latest patents include a closed-system manufacturing process for CAR-T cells. This invention relates to methods and compositions for making genetically modified T cells. In some embodiments, CD4+ and CD8+ T cells are cultured in a single serum-free volume. Additionally, co-cultured CD4+ and CD8+ T cells can be transduced with a lentiviral vector, allowing for the harvesting of a population of transduced T cells within a shorter period than conventional methods. Another significant patent is for matrix metalloproteinase cleavable protein polymers for cancer gene therapy. This delivery system includes a recombinantly synthesized protein polymer with protease cleavage sites, such as matrix metalloproteinase responsive sequences engineered within the protein polymer. This system may be utilized to treat cancer, wounds, or pathological conditions in tissues that express excess protease relative to healthy tissue.
Career Highlights
Gustafson has worked with esteemed organizations such as Seattle Children's Hospital and the University of Utah Research Foundation. His experience in these institutions has allowed him to collaborate on groundbreaking research and development projects.
Collaborations
Some of his notable coworkers include Michael C. Jensen and Hamidreza Ghandehari. Their collaborative efforts have contributed to the advancement of innovative therapies in the field of biotechnology.
Conclusion
Joshua Gustafson's contributions to the field of biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to inspire advancements in cancer treatment and gene therapy.