Location History:
- Tampa, FL (US) (2010)
- St. Louis, MO (US) (2013)
Company Filing History:
Years Active: 2010-2013
Title: Joseph Wahle: Innovator in NK Cell Activation and Stem Cell Transplantation
Introduction
Joseph Wahle is a notable inventor based in St. Louis, MO (US). He has made significant contributions to the field of medical science, particularly in the areas of natural killer (NK) cell activation and stem cell transplantation. With a total of 2 patents, Wahle's work is paving the way for advancements in therapeutic techniques.
Latest Patents
Wahle's latest patents include a method of activating NK cells and a method for enhancing the efficacy of autologous stem cell transplants. The first patent provides a method for mediating hypo-activation of NK cells through the administration of broad-acting phosphatase inhibitors, such as sodium orthovanadate and SHP specific inhibitors like NSC119910. The second patent focuses on the inhibition of SHIP expression or function to improve the outcomes of stem cell transplants. This invention aims to temporarily expand and mobilize the hematopoietic stem cell compartment, assisting in leukapheresis and promoting recovery after myeloablation treatments.
Career Highlights
Wahle is affiliated with the University of South Florida, where he continues to engage in innovative research. His work has garnered attention for its potential to improve patient outcomes in stem cell therapies and cancer treatments.
Collaborations
Wahle has collaborated with notable colleagues, including William Garrow Kerr and Caroline Desponts. These partnerships have contributed to the advancement of his research and the development of his patented methods.
Conclusion
Joseph Wahle's contributions to the fields of NK cell activation and stem cell transplantation highlight his role as an influential inventor. His innovative patents are set to make a significant impact on medical treatments and patient care.