This inventor holds 1 USPTO granted patent and 1 published patent application and 1 EPO patent. Top assignee: Adaptive Phage Therapeutics, Inc.. Active years: 2024.
Company Filing History:
Years Active: 2024
Title: Joseph Robert Fackler: Innovator in Bacteriophage Purification
Introduction
Joseph Robert Fackler is a notable inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of bacteriophage research, particularly in the purification of phage particles. His innovative methods have potential applications in therapeutic settings, showcasing the importance of his work in modern medicine.
Latest Patents
Fackler holds a patent for a "Method for purification of bacteriophage particles." This patent describes a technique for recovering viable phage from crude preparations, such as lysates resulting from amplification in bacterial cell cultures. The method is designed to be universal, applicable to a wide range of phage species and strains. The resulting phage product is characterized by an acceptably low endotoxin titer, specifically less than 500 EU/ml, and a sufficiently high phage titer, exceeding 1×10 PFU/ml, making it suitable for therapeutic applications.
Career Highlights
Fackler is associated with Adaptive Phage Therapeutics, Inc., where he continues to advance research in bacteriophage therapy. His work is pivotal in developing treatments that utilize phages to combat bacterial infections, an area of growing importance in the face of antibiotic resistance.
Collaborations
Fackler collaborates with esteemed colleagues, including Carl Merril and Jarrar Haider. Their combined expertise enhances the research and development efforts at Adaptive Phage Therapeutics, Inc.
Conclusion
Joseph Robert Fackler's contributions to bacteriophage purification represent a significant advancement in therapeutic applications. His innovative methods and collaborations continue to pave the way for new treatments in the medical field.