Company Filing History:
Years Active: 1981-1983
Title: The Innovative Contributions of Joseph Limet
Introduction
Joseph Limet is a notable inventor based in Marchin, Belgium. He has made significant contributions to the field of immunoassays, holding two patents that showcase his innovative approach to medical diagnostics. His work has implications for improving the accuracy and reliability of immunoassays used in various applications.
Latest Patents
Limet's latest patents include "Immunoassays using F(AB').sub.2 fragments" and "Insolubilized proteins and immunoassays utilizing them." The first patent describes a method for conducting immunoassays for antigens or haptens using F(ab').sub.2 fragments instead of traditional immunoglobulin antibodies. This approach effectively avoids interference from endogenous RF and Clq in the fluid under assay, eliminating the need for pre-treatment of the fluid. The assays can be of various types, including latex agglutination and competitive binding assays. The second patent focuses on creating insolubilized antibodies, F(ab').sub.2 fragments, and protein antigens by coupling them to a water-insoluble substrate using a bridging agent that covalently binds to sulfur atoms in the antibody or protein. This innovative method enhances the effectiveness of immunoassays utilizing these insolubilized reagents.
Career Highlights
Joseph Limet has had a distinguished career, working with Technicon Instruments Corporation, where he has been able to apply his expertise in immunoassays. His innovative work has contributed to advancements in diagnostic technologies, making a significant impact in the field.
Collaborations
Limet has collaborated with notable colleagues, including Cesar L Cambiaso and Claude H Moussebois. These collaborations have likely enriched his research and contributed to the development of his patents.
Conclusion
Joseph Limet's contributions to the field of immunoassays through his innovative patents demonstrate his commitment to advancing medical diagnostics. His work continues to influence the industry and improve the accuracy of diagnostic tests.