Joseph K Burkholder

Title: Joseph K Burkholder: Innovator in Genetic Transformation

Introduction

Joseph K Burkholder is a notable inventor based in Madison, WI (US). He has made significant contributions to the field of genetic transformation, holding a total of 2 patents. His innovative methods and apparatus have advanced the capabilities of genetic engineering, particularly in mammalian cells.

Latest Patents

Burkholder's latest patents include a method for particle-mediated transformation of mammalian unattached cells. This method involves preparing copies of a nucleic acid construct and coating them onto biologically inert carrier particles. The process begins with isolating mammalian unattached cells in a liquid suspension, which is then spread onto a target surface. The cells are bombarded with the construct-coated particles, allowing for the genetic transformation of the cells. Another significant patent is an apparatus designed for the particle-mediated genetic transformation of organisms in vivo. This apparatus consists of a support unit and a hand unit, which is conveniently sized for easy manipulation. It is particularly effective for transforming somatic cells in whole animals or humans.

Career Highlights

Throughout his career, Burkholder has worked with various companies, including Agracetus. His work has focused on developing innovative solutions for genetic transformation, contributing to advancements in biotechnology.

Collaborations

Burkholder has collaborated with notable individuals in his field, including Dennis E McCabe and Ning-Sun Yang. These collaborations have further enriched his research and development efforts.

Conclusion

Joseph K Burkholder's contributions to genetic transformation through his patents and collaborations highlight his role as an innovator in the field. His work continues to influence advancements in biotechnology and genetic engineering.