Joseph H Grossman

Title: Joseph H Grossman: Innovator in Pharmaceutical Chemistry

Introduction

Joseph H Grossman is a notable inventor based in Syracuse, NY (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly in the production of antibiotics. With a total of 2 patents, his work has had a lasting impact on the industry.

Latest Patents

Grossman's latest patents include innovative processes for the production of amoxicillin and 7-aminocephalosporanic acids. The first patent focuses on enhancing the efficiency and purity of amoxicillin production through a new recovery process. This process involves isolating solid amoxicillin hydrochloride from the acylation reaction mixture, which can then be easily converted to amoxicillin trihydrate. The second patent addresses the preparation of 7-aminocephalosporanic acids, valuable intermediates in the synthesis of semi-synthetic cephalosporins. This invention claims the use of dicyclohexylamine or diisopropylamine as a substitute for a tertiary amine acid scavenger in the preparation process.

Career Highlights

Joseph H Grossman has had a distinguished career at Bristol-Myers Company, where he has been instrumental in advancing pharmaceutical manufacturing techniques. His innovative approaches have contributed to the development of essential antibiotics that are widely used in medical treatments today.

Collaborations

Throughout his career, Grossman has collaborated with several talented individuals, including Glenn A Hardcastle, Jr and David A Johnson. These collaborations have fostered a creative environment that has led to groundbreaking advancements in pharmaceutical chemistry.

Conclusion

Joseph H Grossman is a prominent figure in the field of pharmaceutical innovation, with a focus on antibiotic production. His patents reflect a commitment to improving efficiency and product quality in the industry. His contributions continue to influence the development of essential medications.