Joseph F Krebs

Title: Joseph F. Krebs: Innovator in Apoptosis Research

Introduction

Joseph F. Krebs is a notable inventor based in San Diego, CA, who has made significant contributions to the field of apoptosis research. With a focus on developing innovative solutions for treating various pathological disorders, he holds 2 patents that showcase his expertise and dedication to advancing medical science.

Latest Patents

Krebs' latest patents include groundbreaking work on "Membrane derived caspase-3, compositions comprising the same and methods of use therefor." This invention provides isolated nucleic acids encoding a novel membrane-derived caspase-3 and the polypeptides expressed from it. The nucleic acid expression vectors can be introduced into host cells as a gene delivery vehicle. Additionally, the methods outlined in this patent aim to treat pathological disorders caused by altered apoptosis, such as autoimmune diseases, cancer, viral infections, and bacterial infections. Another significant patent focuses on "Methods for detecting membrane derived caspase activity." This invention provides methods for identifying membrane-derived apoptotic activity and offers drug discovery methods for screening compounds that inhibit or enhance this activity.

Career Highlights

Joseph F. Krebs is currently associated with Idun Pharmaceuticals, Inc., where he continues to push the boundaries of research in apoptosis and its implications for various diseases. His work is instrumental in developing therapeutic strategies that can significantly impact patient care.

Collaborations

Krebs has collaborated with esteemed colleagues, including Lawrence C. Fritz and Anupama Srinivasan, to further enhance the scope and impact of his research.

Conclusion

Joseph F. Krebs stands out as an influential inventor in the field of apoptosis research, with his innovative patents paving the way for new therapeutic approaches. His contributions are vital for advancing our understanding and treatment of diseases related to apoptosis.