Joseph Edwin Low

Title: Joseph Edwin Low: Innovator in Antibody Development

Introduction

Joseph Edwin Low is a prominent inventor based in Ann Arbor, MI (US), known for his significant contributions to the field of biotechnology. He holds a total of 10 patents, showcasing his innovative spirit and dedication to advancing medical science.

Latest Patents

One of his latest patents focuses on antibodies to M-CSF (Macrophage Colony-Stimulating Factor). This invention relates to antibodies and antigen-binding portions that specifically bind to human M-CSF and function to inhibit its activity. The patent also covers human anti-M-CSF antibodies and various forms of these antibodies, including chimeric, bispecific, and single-chain antibodies. Additionally, it includes isolated heavy and light chain immunoglobulins derived from human anti-M-CSF antibodies, along with nucleic acid molecules encoding these immunoglobulins. The invention outlines methods for producing human anti-M-CSF antibodies, compositions containing these antibodies, and their applications in diagnosis and treatment. Furthermore, it provides gene therapy methods utilizing nucleic acid molecules encoding the immunoglobulin molecules and discusses the use of transgenic animals and plants in this context.

Career Highlights

Throughout his career, Joseph Edwin Low has worked with notable companies, including Warner-Lambert Company and Amgen Fremont Inc. His work in these organizations has contributed to the development of innovative biotechnological solutions.

Collaborations

Joseph has collaborated with esteemed colleagues such as Madhav Narasimha Devalaraja and Vahe Bedian, further enhancing his research and development efforts in the field.

Conclusion

Joseph Edwin Low's contributions to antibody development and biotechnology have made a significant impact on medical research and treatment options. His innovative patents and collaborations reflect his commitment to advancing science and improving healthcare outcomes.