Joseph DeAngelo

Title: Innovations by Joseph DeAngelo

Introduction

Joseph DeAngelo is a notable inventor based in Hamtramck, MI (US). He holds a total of five patents that focus on improving therapeutic effectiveness in various medical treatments. His work primarily revolves around the use of nitric oxide inhibitors in cancer therapy and tissue vascularization disorders.

Latest Patents

DeAngelo's latest patents include methods for enhancing the therapeutic effectiveness of treatments for inappropriate tissue vascularization disorders. One significant invention involves the use of nitric oxide scavengers or NO synthase inhibitors as adjuncts to treatment. Another patent focuses on utilizing these inhibitors as antitumor therapies to reduce tumor blood flow and oxygenation. His inventions also explore the administration of nitric oxide synthase substrates to selectively inhibit tumor perfusion while restoring normal blood flow. Notably, one example demonstrates that the administration of cell-free hemoglobin, a nitric oxide scavenger, in conjunction with mitomycin C, significantly delays tumor growth in human tumor xenografts.

Career Highlights

Throughout his career, Joseph DeAngelo has worked with reputable institutions such as Duke University and Apex Bioscience, Inc. His contributions to the field of medical research have been significant, particularly in the area of cancer treatment.

Collaborations

DeAngelo has collaborated with notable individuals in his field, including Joseph Bonaventura and Mark W. Dewhirst. These collaborations have likely enhanced the impact of his research and innovations.

Conclusion

Joseph DeAngelo's work in the field of medical inventions showcases his commitment to improving therapeutic outcomes for patients. His innovative approaches to cancer treatment and tissue vascularization disorders highlight the importance of research and development in medicine.