Company Filing History:
3 out of 832,912 Years Active: 2002-2005
Title: Joseph Atabekov: Innovator in Gene Expression Technologies
Introduction
Joseph Atabekov is a prominent inventor based in Moscow, Russia. He has made significant contributions to the field of genetic engineering, particularly in the area of gene expression in eukaryotic cells. With a total of 3 patents, Atabekov's work has the potential to advance biotechnological applications in various organisms.
Latest Patents
Atabekov's latest patents include innovative methods for coexpression of multiple genes in eukaryotic cells. A primary objective of this invention is to provide a method that enables the simultaneous coexpression of two or more desired genes in plant, animal, or yeast cells. This method utilizes sequence elements derived from RNAs of a tobamovirus, which are positioned upstream of the MP gene or CP gene, referred to as IRES and IRES, respectively. The invention involves constructing a recombinant nucleic acid sequence that includes a specific transcriptional promoter, a first gene expressible in eukaryotic cells linked to the promoter, and a second gene expressible in eukaryotic cells, strategically placed under the transcriptional control of the IRES sequence. This innovative approach allows for enhanced gene expression through the production of a primary chimeric RNA transcript in positive sense polarity.
Another notable patent focuses on the enhancement of gene expression in plants. This invention aims at the super-expression of foreign genes in transgenic cells by combining several trans- and cis-acting genetic elements of viral origin within a single cDNA construct and respective RNA transcript.
Career Highlights
Throughout his career, Joseph Atabekov has established himself as a leading figure in genetic research. His work has been instrumental in developing methods that improve gene expression, which can have far-reaching implications in agriculture and medicine.
Collaborations
Atabekov has collaborated with notable colleagues such as Timo Korpela and Yurii Dorokhov. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Joseph Atabekov's innovative work in gene expression technologies showcases his commitment to advancing the field of genetic engineering. His contributions have the potential to significantly impact various applications in biotechnology and beyond.