Joseph A Holden

Title: Joseph A. Holden: Innovator in Nucleic Acid Analysis

Introduction

Joseph A. Holden is a notable inventor based in Salt Lake City, Utah. He has made significant contributions to the field of nucleic acid analysis, particularly through his innovative methods involving dsDNA binding dyes. His work has implications for various applications in molecular biology and genetics.

Latest Patents

Joseph A. Holden holds a patent for "Nucleic acid melting analysis with saturation dyes." This patent describes methods for nucleic acid analysis wherein a target nucleic acid is mixed with a dsDNA binding dye to form a mixture. Optionally, an unlabeled probe can be included in the mixture. A melting curve is generated for the target nucleic acid by measuring fluorescence from the dsDNA binding dye as the mixture is heated. The patent also covers dyes for use in nucleic acid analysis and methods for making these dyes.

Career Highlights

Throughout his career, Joseph A. Holden has worked with esteemed organizations such as the University of Utah Research Foundation and Idaho Technology, Inc. His experience in these institutions has allowed him to advance his research and contribute to the scientific community.

Collaborations

Joseph has collaborated with notable individuals in his field, including Carl Thomas Wittwer and Luming Zhou. These collaborations have further enriched his research and innovation in nucleic acid analysis.

Conclusion

Joseph A. Holden's contributions to nucleic acid analysis through his patented methods and collaborative efforts highlight his role as an influential inventor in the scientific community. His work continues to impact the field of molecular biology.