Location History:
- Zelienople, PA (US) (2002)
- Wexford, PA (US) (2000 - 2003)
Company Filing History:
Years Active: 2000-2003
Title: Joseph A. Corella, II: Innovator in Chemical Reactions
Introduction
Joseph A. Corella, II is a notable inventor based in Wexford, PA (US). He has made significant contributions to the field of chemistry, particularly in the area of enantioselectivity in reduction reactions. With a total of 4 patents to his name, Corella's work has implications for various applications in chemical synthesis.
Latest Patents
One of Corella's latest patents focuses on increasing enantioselectivity in reductions with borane reagents. This method involves a reduction reaction of a prochiral substrate using a borane reagent that includes a borohydride species. The process is catalyzed by a chiral catalyst and maintains the concentration of borohydride species in the borane reagent below approximately 0.005 M during the reduction. Additionally, he has developed a method to reduce the detrimental effect of the borohydride species on enantioselectivity by adding a Lewis acid. This innovative approach can be applied to prochiral substrates such as ketones, utilizing a chiral oxazaborolidine as the catalyst.
Career Highlights
Corella is currently associated with Mine Safety Appliances Company, where he continues to apply his expertise in chemical reactions. His work has not only advanced the field but has also contributed to the safety and efficiency of chemical processes.
Collaborations
Corella has collaborated with notable colleagues, including Elizabeth R. Burkhardt and Karl Matos, enhancing the scope and impact of his research.
Conclusion
Joseph A. Corella, II exemplifies innovation in the field of chemistry through his patents and collaborative efforts. His contributions to enantioselectivity in chemical reactions are paving the way for advancements in the industry.