Company Filing History:
Years Active: 1996-1999
Title: Innovations by Josefino C Sagala
Introduction
Josefino C Sagala is a notable inventor based in San Jose, CA, who has made significant contributions to the field of flow cytometry. He holds 2 patents that focus on methods for analyzing blood cells, particularly nucleated red blood cells and white blood cells. His work is essential for advancements in medical diagnostics and research.
Latest Patents
One of his latest patents is titled "Method for simultaneous analysis of cell viability, nucleated red blood." This method provides a quantitative flow cytometric analysis of nucleated red blood cells (NRBC), white blood cells (WBC), and damaged WBCs. The process involves mixing a whole blood sample with a reagent system that lyses RBCs and NRBCs while preserving WBC cellular membranes. The method utilizes a membrane-impermeant nucleic acid stain to identify NRBC nuclei and damaged WBCs, followed by flow cytometric light measurements to differentiate and quantify the various cell types.
Another significant patent is "Method for rapid and simultaneous analysis of nucleated red blood cells." This invention describes a method and device for the flow cytometric analysis of NRBC and WBC in whole blood samples. The technique includes lysing RBCs and NRBC cytoplasm to expose NRBC to a vital nuclear stain while preventing the stain from permeating WBCs. The resulting signals are analyzed to construct a three-dimensional plot that differentiates NRBC and WBC, allowing for accurate cell counting.
Career Highlights
Josefino C Sagala is currently employed at Abbott Laboratories Corporation, where he continues to innovate in the field of medical diagnostics. His work has contributed to the development of advanced techniques that enhance the accuracy and efficiency of blood cell analysis.
Collaborations
He has collaborated with notable colleagues such as Young Ran Kim and Michael W Yee, furthering the impact of his research and innovations in the medical field.
Conclusion
Josefino C Sagala's contributions to flow cytometry and blood cell analysis are invaluable. His patents reflect a commitment to improving medical diagnostics, showcasing his role as a leading inventor in this critical area of research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.