Berlin, Germany

Josef Klosa


Average Co-Inventor Count = 2.0

ph-index = 2

Forward Citations = 4(Granted Patents)


Company Filing History:


Years Active: 1977

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2 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Josef Klosa

Introduction

Josef Klosa, an accomplished inventor based in Berlin, Germany, has made significant strides in the field of pharmaceutical chemistry with his innovative approaches to central nervous system (CNS) stimulants. With a total of two patents, Klosa demonstrates a commitment to advancing medical science through his creative processes and potent compounds.

Latest Patents

Josef Klosa's latest patents revolve around the development of 4,4-Diarylpiperidines, specifically focusing on processes to create highly effective CNS stimulants. These compounds, particularly 4,4-diphenylpiperidine, can be either substituted or unsubstituted at the 1-position of the piperidine nucleus. Klosa's formulations highlight the effectiveness of these compounds as superior alternatives to known amphetamine-type stimulants. He describes a novel process involving the reaction of 4-aryl-4-hydroxypiperidine compounds, which may be substituted at their 3-position with an aroyl group, with an aromatic hydrocarbon like benzene in the presence of a Friedel-Crafts-type catalyst.

Career Highlights

Klosa is associated with Byk Gulden Lomberg Chemische Fabrik GmbH, where he collaborates with a team dedicated to advancing chemical technologies. His work has not only expanded the understanding of CNS stimulants but also opened new avenues for therapeutic applications in treating various conditions.

Collaborations

Throughout his career, Klosa has collaborated with other notable professionals, including Gerhard Hackmack and Heinz Gunter Menge. These collaborations underline the importance of teamwork and shared expertise in enhancing innovation and achieving groundbreaking results in pharmaceutical developments.

Conclusion

Josef Klosa’s contributions to the field of pharmaceuticals through his patents and collaborative efforts illustrate his role as a key inventor in drug development. His innovative processes for creating effective CNS stimulants position him as a notable figure in the ongoing pursuit of medical advancements that can benefit society.

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