Company Filing History:
Years Active: 2011-2012
Title: The Innovative Contributions of Josef Cinibulk in Pharmaceutical Development
Introduction: Josef Cinibulk is a notable inventor based in Prague, Czech Republic, recognized for his significant contributions to pharmaceutical innovations. With a total of two patents to his name, Cinibulk has developed methods that enhance the preparation of essential drugs, demonstrating his expertise in the field of chemistry and pharmacology.
Latest Patents: Josef Cinibulk's latest patents focus on advanced methodologies for synthesizing the hydrochloride salt of duloxetine, a medication used for treating major depressive disorder and generalized anxiety disorder. His first patent outlines a method for preparing (S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride through a reaction of duloxetine base with concentrated hydrochloric acid in ethylmethylketone and the subsequent crystallization of the hydrochloride salt. The second patent describes a comprehensive method for creating (S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine and its pharmaceutically acceptable salts, detailing multi-step processes involving various chemical reactions, isolations, and conversions essential for pharmaceutical applications.
Career Highlights: Cinibulk is currently associated with Zentiva, a prominent pharmaceutical company known for its commitment to producing high-quality generic medications. His work has not only advanced the field but has also contributed to the availability of effective treatments for patients.
Collaborations: Throughout his career, Josef Cinibulk has collaborated with distinguished coworkers such as Ludek Ridvan and Kamal Jarrah. These partnerships have fostered an innovative environment, leading to the successful development of new pharmaceutical products and methodologies.
Conclusion: Josef Cinibulk exemplifies the role of inventors in the pharmaceutical industry, with his innovative methods paving the way for more effective treatments. His patents reflect a deep understanding of chemical processes and a commitment to enhancing patient care through pharmaceutical advancements.