Josee Laliberte

Title: The Innovative Contributions of Josee Laliberte

Introduction

Josee Laliberte is a notable inventor based in Chapel Hill, NC (US). She has made significant contributions to the field of genetic engineering, particularly through her innovative patent related to cytidine deaminase.

Latest Patents

Laliberte holds a patent for "Cytidine deaminase cDNA as a positive selectable marker for gene." This invention involves a DNA sequence for the human cytidine deaminase that has been engineered into an eukaryotic expression vector. This advancement allows for the expression of cytidine deaminase in mammalian cells, which confers resistance to cytosine nucleoside analogs, such as cytosine arabinoside. The expression of cytidine deaminase protects cells from the toxic effects of these analogs, providing potential applications in gene therapy for malignant, immune, and viral diseases. Additionally, a bacterial expression vector containing the gene can be utilized to produce cytidine deaminase in large quantities.

Career Highlights

Josee Laliberte is associated with the Hospital Sainte-Justine, where she continues to contribute to her field. Her work has implications for advancing gene therapy techniques and improving treatment options for various diseases.

Collaborations

Laliberte has collaborated with notable colleagues, including Richard Lewis Momparler and Denis Cournoyer. These partnerships have likely enhanced her research and development efforts in genetic engineering.

Conclusion

Josee Laliberte's innovative work in genetic engineering, particularly her patent on cytidine deaminase, showcases her significant contributions to the field. Her efforts have the potential to impact gene therapy and improve treatment options for various diseases.