Jorge Castro Velazco

Title: The Innovations of Jorge Castro Velazco

Introduction

Jorge Castro Velazco is a notable inventor based in La Habana, Cuba. He has made significant contributions to the field of biotechnology, particularly in the development of vaccines. His work focuses on combating the dengue virus, which poses a serious health threat in many tropical regions.

Latest Patents

Jorge Castro Velazco holds 1 patent for a dengue virus vaccine composition. This innovative vaccine comprises at least one antigen based on the dengue virus (DV) capsid protein and the oligonucleotide identified as SEQ ID NO 1. The composition includes a fusion protein formed by the DV2 capsid and domain III of the envelope protein of the same serotype. This formulation has been shown to elicit higher levels of cellular immune response and protection in mice compared to previous formulations. The efficacy of these compositions has also been demonstrated in non-human primates. The vaccine compositions can be monovalent, bivalent, or tetravalent and are designed to induce a functional immune response to the four viral serotypes.

Career Highlights

Throughout his career, Jorge has worked with prominent institutions such as the Centro de Ingeniería Genética y Biotecnología. His research has focused on developing effective vaccine strategies to combat viral infections, showcasing his commitment to public health and scientific advancement.

Collaborations

Jorge has collaborated with several professionals in his field, including Lisset Hermida Cruz and Lázaro Gil González. These partnerships have contributed to the success of his research and the development of innovative solutions in biotechnology.

Conclusion

Jorge Castro Velazco's contributions to vaccine development, particularly for the dengue virus, highlight his role as a significant inventor in the field of biotechnology. His innovative approaches and collaborations continue to pave the way for advancements in public health.