Company Filing History:
1 out of 832,812 Years Active: 1999
Title: Innovations in Gene Therapy: The Contributions of Jorg Tatzelt
Introduction
Jorg Tatzelt, an innovative inventor based in San Francisco, CA, has made significant strides in the field of gene therapy with his unique approaches to correcting genetic defects. His work addresses conformationally defective proteins that lead to various phenotypic defects, paving the way for advancements in the treatment of genetic disorders.
Latest Patents
Jorg Tatzelt holds a patent for the invention titled "Correction of genetic defects using chemical chaperones." This patent outlines methods to improve phenotypic defects caused by conformationally defective target proteins. The invention emphasizes the use of protein stabilizing agents, such as dimethylsulfoxide (DMSO), deuterated water, and trimethylamine N-oxide (TMAO), to enhance the functionality of defective proteins. Notable examples of target proteins addressed in this patent include the cystic fibrosis transmembrane conductance regulator (CFTR) and prion proteins. Additionally, the patent includes methodologies for detecting protein stabilizing agents and identifying pathological conditions caused by improper protein folding.
Career Highlights
Throughout his career, Jorg Tatzelt has focused on enhancing the understanding and treatment of genetic disorders through innovative methods. His dedication to research and development in this critical area demonstrates his commitment to improving patient outcomes at a cellular level.
Collaborations
Collaboration is a cornerstone of Jorg Tatzelt's innovative work. He has worked alongside esteemed colleagues, including William J Welch and C Randell Brown, fostering an environment of shared knowledge and expertise that amplifies their collective impact on the field.
Conclusion
In conclusion, Jorg Tatzelt stands out as a pioneering inventor whose patent for correcting genetic defects using chemical chaperones could revolutionize treatments for genetic diseases. His collaborative efforts and innovative mindset continue to contribute significantly to advancements in gene therapy and improve the lives of many individuals affected by genetic disorders.