Company Filing History:
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1 out of 1 Years Active: 2000
Title: Joost Verhaagen: Innovator in Neuronal Gene Therapy
Introduction
Joost Verhaagen is a prominent inventor based in Utrecht, Netherlands. He is known for his significant contributions to the field of neuronal gene therapy. His work focuses on the expression of growth-associated proteins, which play a crucial role in nerve regeneration and repair.
Latest Patents
Verhaagen holds a patent for the "Expression of growth associated protein B-50/GAP-43 in vitro and in vivo." This invention relates to a viral vector capable of transferring and expressing the B-50/GAP-43 protein in neuronal target cells of a mammalian host. The viral vector comprises a recombinant DNA molecule that includes the B-50/GAP-43 gene, which is operably associated with a promoter that controls short-term, high-level expression of the gene. The invention also provides a method for treating nerve damage by introducing the vector into damaged nerve tissue, enhancing the survival of cultured neurons for transplantation.
Career Highlights
Throughout his career, Joost Verhaagen has worked with esteemed institutions such as The Rockefeller University and the Rudolf Magnus Institute. His research has significantly advanced the understanding of neuronal growth and repair mechanisms.
Collaborations
One of his notable collaborators is Michael G Kaplitt, with whom he has worked on various projects related to gene therapy and neuronal regeneration.
Conclusion
Joost Verhaagen's innovative work in the field of neuronal gene therapy has the potential to transform treatments for nerve damage. His contributions continue to inspire advancements in medical research and therapeutic applications.