Company Filing History:
Years Active: 2017-2024
Title: Innovations of Jonathan Stites in Nucleic Acid Technology
Introduction
Jonathan Stites is a prominent inventor based in Santa Cruz, CA (US). He has made significant contributions to the field of nucleic acid technology, holding a total of 5 patents. His work focuses on advancing methods for nucleic acid sequence assembly, which is crucial for various applications in genomics and molecular biology.
Latest Patents
Among his latest patents, one notable invention is related to "Tagging nucleic acids for sequence assembly." This patent discloses various approaches for generating long-distance contiguity information to facilitate contig assembly and phase determination. In this method, nucleic acids are assembled into complexes using binding moieties. When the nucleic acid backbones are cleaved, the ensuing fragments remain bound, allowing for effective tagging and ligation. The exposed ends are tagged and ligated either to one another or to tagging moieties such as oligo labels. The ligated junctions are sequenced, and the sequence information is utilized to assemble contigs into common scaffolds or to assign phase information. Various approaches to tagging the exposed ends are presented in this patent.
Another significant patent by Jonathan Stites is focused on "Nucleic acid sequence assembly." This invention discloses compositions, systems, and methods related to sequence assembly. It emphasizes the nucleic acid sequence assembly of single reads and contigs into larger contigs and scaffolds through the use of read pair sequence information. This information is indicative of nucleic acid sequence phase or physical linkage, which is essential for accurate genomic analysis.
Career Highlights
Jonathan Stites is currently associated with Dovetail Genomics, LLC, where he continues to innovate in the field of genomics. His work has been instrumental in developing technologies that enhance the efficiency and accuracy of nucleic acid sequencing.
Collaborations
He collaborates with notable colleagues such as Nicholas H Putnam and Brandon J Rice, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Jonathan Stites is a key figure in the advancement of nucleic acid technology, with a focus on improving sequence assembly methods. His patents reflect a commitment to enhancing genomic research and applications. His contributions are paving the way for future innovations in the field.
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