Jonathan S Duke-Cohan

Title: Innovations of Jonathan S Duke-Cohan

Introduction

Jonathan S Duke-Cohan is a notable inventor based in Cambridge, MA (US). He has made significant contributions to the field of immunology, holding three patents that reflect his innovative work. His research focuses on enhancing immune responses and understanding the biochemical properties of specific proteins.

Latest Patents

One of his latest patents is titled "Regulation of immune responses by attractin." This invention features attracting polypeptides and nucleic acids encoding them, which are useful for enhancing immune responses. Another significant patent is related to the "Form of dipeptidylpeptidase IV (CD26) found in human serum." This patent discloses a soluble form of CD26 isolated from human serum, which shares similar enzymatic and antigenic properties with the membrane form. However, there are distinct biochemical differences, including a molecular weight of 175 kDa for the soluble form, in contrast to the 105 kDa molecular weight of the membrane form. Notably, the soluble form retains functional dipeptidylpeptidase IV activity and can costimulate the T lymphocyte response to recall antigen.

Career Highlights

Jonathan S Duke-Cohan is affiliated with the Dana-Farber Cancer Institute Inc., where he continues to advance his research in immunology. His work has contributed to a deeper understanding of immune responses and the role of specific proteins in these processes.

Collaborations

He has collaborated with esteemed colleagues such as Stuart F Schlossman and Chikao Morimoto, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Jonathan S Duke-Cohan's innovative work in immunology, highlighted by his patents and collaborations, showcases his commitment to advancing scientific knowledge and improving immune response mechanisms. His contributions are significant in the ongoing research in this vital field.