This inventor holds 2 USPTO granted patents. Top assignees: Harvard College, The Broad Institute, Inc.. Active years: 2026.
Company Filing History:
2 out of 3,071 
1 out of 483 
Years Active: 2026
Title: Innovations of Jonathan MA Levy in Gene Editing
Introduction
Jonathan MA Levy is an accomplished inventor based in Cambridge, MA (US). He has made significant contributions to the field of gene editing, particularly through his innovative approaches to delivering nucleobase editors. His work is characterized by a focus on enhancing the efficiency and effectiveness of genetic modifications.
Latest Patents
Jonathan MA Levy holds a patent for "AAV delivery of nucleobase editors." This patent describes methods for delivering 'split' Cas9 protein or nucleobase editors into cells using recombinant adeno-associated virus (rAAV). The invention involves splitting the Cas9 protein or nucleobase editor into two sections, each fused with parts of an intein system. Upon co-expression, these sections are ligated together through intein-mediated protein splicing. This method provides a novel approach to gene editing, allowing for precise modifications at the genetic level.
Career Highlights
Levy's career is marked by his association with Harvard College, where he has been able to leverage the institution's resources and collaborative environment to advance his research. His work has garnered attention for its potential applications in various fields, including medicine and biotechnology.
Collaborations
Throughout his career, Jonathan has collaborated with notable researchers such as Wei Hsi Yeh and David R Liu. These collaborations have enriched his work and contributed to the development of innovative solutions in gene editing.
Conclusion
Jonathan MA Levy's contributions to the field of gene editing through his patent on AAV delivery of nucleobase editors exemplify the impact of innovative thinking in science. His work continues to pave the way for advancements in genetic engineering and therapeutic applications.