Location History:
- Bookline, MA (US) (1999)
- Brookline, MA (US) (1997 - 2014)
Company Filing History:
Years Active: 1997-2014
Title: Innovations and Contributions of Jonathan H Dinsmore
Introduction
Jonathan H Dinsmore is a notable inventor based in Brookline, MA (US), recognized for his significant contributions to medical technology. With a total of 17 patents to his name, Dinsmore has focused on advancing treatments for heart disease and improving methods for storing neural cells.
Latest Patents
One of Dinsmore's latest patents is titled "Cellular cardiomyoplasty as supportive therapy in patients with heart disease." This invention provides a system for treating heart disease as a 'bridge to recovery' using cellular cardiomyoplasty. The system is particularly useful in selecting and treating patients with damaged myocardium due to coronary artery disease, myocardial infarction, congestive heart failure, and ischemia. Based on various clinical criteria, a patient is selected and optionally treated using cellular cardiomyoplasty to improve the patient's cardiac function. The cardiomyoplasty may be combined with other treatments such as medications or left ventricular assist devices. Preferably, the cellular cardiomyoplasty eliminates the need for invasive surgery such as bypass grafting or cardiac transplantation. The invention also provides kits for use in selecting and treating patients using the inventive method.
Another significant patent involves "Methods for storing neural cells." This invention pertains to improved methods for storing neural cells, preferably dissociated neural cells, prior to their use in transplantation. One embodiment focuses on methods for storing the neural cells in medium lacking added buffer or added protein. Other embodiments feature neural cells that are maintained at 4°C prior to cryopreservation and have comparable viability and/or functionality to freshly harvested cells. Additionally, methods for storing and/or transplantation of porcine neural cells are described.
Career Highlights
Dinsmore has worked with various companies, including Diacrin, Inc., where he has contributed to innovative projects in the medical field. His work has had a lasting impact on the development of therapies aimed at improving patient outcomes.
Collaborations
Throughout his career, Dinsmore has collaborated with notable professionals in the field, including Ole Isacson and Jan Koopmans. These collaborations have further enhanced the scope and effectiveness of his inventions.
Conclusion
Jonathan H Dinsmore's contributions to medical technology through his patents and collaborations have significantly advanced the treatment of heart disease and the storage of neural cells. His innovative work continues to influence the medical field and improve patient care.