Company Filing History:
9 out of 532 
9 out of 3,446 
3 out of 1,217 
Years Active: 1991-2016
Title: Innovations by Inventor Jonathan E. Silver
Introduction
Jonathan E. Silver, an accomplished inventor based in Bethesda, MD, is known for his significant contributions to the field of biotechnology. With a notable portfolio of 14 patents, his work primarily focuses on methods and devices for amplifying nucleic acids, which play a crucial role in genetic research and diagnostics.
Latest Patents
His latest patents exhibit cutting-edge techniques in nucleic acid amplification. One of his notable inventions is a "Device and method for amplifying target nucleic acid." This innovative method involves introducing a sample containing target nucleic acids into a flow channel of a planar fluidic assembly. The device enhances the amplification of nucleic acids through the strategic placement of primers along the channel. The method not only produces amplified products but also allows for the detection of localized accumulation of these products within the flow channel.
Another significant patent is the "Method for detecting the presence of a target nucleic acid sequence in a sample." This method involves loading a sample into a chamber designed to minimize diffusion, subjecting it to an amplification step, and determining the presence of a target nucleic acid. The use of a microfluidic device is essential in this process, as it optimally positions the amplification targeting reagent for effective detection.
Career Highlights
Throughout his career, Jonathan E. Silver has worked with prestigious organizations including Applied Biosystems, LLC and the United States Department of Health and Human Services. His contributions in these roles have significantly impacted the advancement of molecular diagnostics and biotechnological applications.
Collaborations
In his endeavors, Silver has collaborated with notable colleagues such as James F. Brown and Olga V. Kalinina. These partnerships have fostered innovative ideas and enhanced the development of various technologies within the realm of molecular biology.
Conclusion
Jonathan E. Silver's innovative approaches to nucleic acid amplification and detection underscore his status as a leading inventor in the biotechnology field. His work continues to influence research and applications in genetic diagnostics, making significant strides towards advancing healthcare technologies.