Jonathan Brumbach

Title: Innovations in Gene Delivery by Inventor Jonathan Brumbach

Introduction

Jonathan Brumbach is an innovative inventor based in Salt Lake City, UT, known for his contributions to the field of gene delivery. With a focus on enhancing nucleotide delivery mechanisms, Brumbach's work has significant implications for biomedical applications.

Latest Patents

Jonathan Brumbach holds a patent for "Cleavable modifications to reducible poly(amido ethylenimine)s to enhance nucleotide delivery." This patent discloses improved poly(amido ethylenimine) copolymers specifically designed for gene delivery. One illustrative embodiment includes polyethylene glycol (PEG) covalently bonded to a branched poly(triethyenetetramine/cystamine bisacrylamide) copolymer (poly(TETA/CBA)). Notably, the polyethylene glycol can be linear or branched. Furthermore, this invention outlines a system where an RGD peptide is covalently bonded to the poly(TETA/CBA)-PEG conjugate, with the potential for novel methods in cellular transfection using these innovative compositions.

Career Highlights

Jonathan is associated with the University of Utah Research Foundation, where he collaborates on cutting-edge research initiatives. His work focuses on advancing the field of gene therapy, providing new pathways for efficient and effective genetic material delivery.

Collaborations

Throughout his career, Jonathan Brumbach has worked alongside notable colleagues, including James W. Yockman and Lane V. Christensen. Their collaborations have fostered a multidisciplinary approach to research, enhancing the impact and reach of their innovations.

Conclusion

Jonathan Brumbach stands out as a significant contributor to the advancements in gene delivery technologies. With his solitary patent and ongoing collaborations, he continues to pave the way for innovative solutions in biomedical research and application. The developments stemming from his expertise are sure to influence the future of gene therapy and associated fields.