This inventor holds 3 USPTO granted patents. Top assignees: The University of North Carolina at Chapel Hill, University of South Florida. Active years: 2009-2015.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Durham, NC (US) (2009)
- Tampa, FL (US) (2011 - 2015)
Company Filing History:
2 out of 1,327 
1 out of 1,990 
Years Active: 2009-2015
Title: Innovations of Jonathan A Harton
Introduction
Jonathan A Harton is an accomplished inventor based in Tampa, FL. He has made significant contributions to the field of biotechnology, particularly in the development of polypeptides and nucleic acids. With a total of 3 patents, his work has the potential to impact various medical applications.
Latest Patents
One of his latest patents is titled "POP2: NKκB-inhibiting polypeptides, nucleic acids and methods of use." This invention introduces a novel pyrin-only protein (POP2), along with polypeptides and nucleic acids that encode them. POP2 is a 294 nt single exon gene located on human chromosome 3, encoding a 97 amino acid protein that shares structural similarities with other pyrin domains. The protein is primarily expressed in peripheral blood leukocytes and exhibits both cytoplasmic and nuclear expression patterns in transfected cells. POP2 has been shown to inhibit TNFα-stimulated and p65 (RelA) induced NF-κB-dependent gene transcription in vitro, potentially influencing the assembly of pyrin-domain dependent complexes.
Another significant invention is related to the CATERPILLER gene family. This patent describes a new family of structurally and functionally related nucleic acids and proteins characterized by distinct structural motifs, including a nucleotide binding domain and leucine-rich repeat domains.
Career Highlights
Throughout his career, Jonathan has worked with prestigious institutions such as the University of North Carolina at Chapel Hill and the University of South Florida. His research has contributed to advancements in understanding the mechanisms of immune response and inflammation.
Collaborations
Jonathan has collaborated with notable colleagues, including Jenny P-y Ting and Michael W Linhoff. Their combined expertise has furthered research in the field of immunology and biotechnology.
Conclusion
Jonathan A Harton is a prominent inventor whose work in biotechnology has led to valuable innovations. His patents, particularly in the area of NF-κB inhibition and the CATERPILLER gene family, showcase his commitment to advancing scientific knowledge and medical applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile