Jon McGinn

Title: Jon McGinn: Innovator in CRISPR Gene Editing

Introduction

Jon McGinn is a prominent inventor based in New York, NY (US), known for his significant contributions to the field of gene editing. He has developed innovative methods that enhance the capabilities of CRISPR technology, which has revolutionized genetic engineering.

Latest Patents

Jon McGinn holds a patent titled "Enhancement of CRISPR gene editing or target destruction by co-expression of heterologous DNA repair protein." This patent provides compositions, methods, and kits aimed at improving CRISPR-based editing of DNA targets by utilizing a CRISPR-associated (Cas) enzyme. The enhancement is achieved by combining the Cas enzyme and a CRISPR targeting RNA with a heterologous DNA repair enzyme, which may include RecBCD, AddAB, or AdnAB. Notably, the heterologous DNA repair enzyme can have inactivated nuclease activity. The method also incorporates the use of a DNA repair template to introduce changes into the edited DNA, and it includes cells that contain components of the improved CRISPR systems, as well as kits for creating such cells.

Career Highlights

Jon McGinn is affiliated with The Rockefeller University, where he conducts his research and development in gene editing technologies. His work has positioned him as a key figure in the advancement of CRISPR applications.

Collaborations

Jon McGinn collaborates with notable scientists in his field, including Luciano Marraffini and Josh Modell. Their combined expertise contributes to the ongoing innovation in gene editing techniques.

Conclusion

Jon McGinn's work in enhancing CRISPR technology exemplifies the potential of innovative approaches in genetic engineering. His contributions are paving the way for future advancements in the field.