Jon H Astle

Title: Jon H Astle: Innovator in Genetic Research

Introduction

Jon H Astle is a notable inventor based in Taunton, MA (US), recognized for his contributions to genetic research. He holds a total of five patents, showcasing his innovative approach to understanding human genes and their implications in medical diagnostics and therapeutics.

Latest Patents

Astle's latest patents include a method for detecting a differentially expressed sequence. This invention pertains to novel human genes, proteins expressed by these genes, and variants of the proteins. It also relates to diagnostic assays and therapeutic agents associated with the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue. Another significant patent is titled "Human genes and gene expression products: II," which shares similar themes of novel human genes and their applications in diagnostics and therapeutics.

Career Highlights

Throughout his career, Jon H Astle has worked with prominent organizations such as Bayer Corporation and the Mayo Foundation for Medical Education and Research. His work in these institutions has significantly contributed to advancements in medical research and genetic studies.

Collaborations

Astle has collaborated with notable colleagues, including Christopher C Burgess and Theodore J Catino, enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Jon H Astle's innovative work in genetic research and his contributions through patents highlight his role as a significant figure in the field. His inventions continue to influence the understanding of human genetics and its applications in medicine.