Location History:
- Malden, MA (US) (2004 - 2006)
- Tampa, FL (US) (2010 - 2017)
Company Filing History:
4 out of 8,373 
3 out of 1,933 
Years Active: 2004-2017
Title: Jon Clarence Antilla: Innovator in Stroke Treatment and Chemical Bond Formation
Introduction
Jon Clarence Antilla is a notable inventor based in Tampa, FL, with a focus on innovative treatments for stroke and advancements in chemical bond formation. He holds a total of 7 patents, showcasing his contributions to the fields of medicine and chemistry.
Latest Patents
Antilla's latest patents include groundbreaking methods for treating stroke using novel sigma agonists. His research presents a method of administering N,N'-di-1-naphthylguanidine HCl (NAGH) and N,N'-di-p-nitrophenylguanidine HCl (NAD) to improve recovery outcomes when administered at delayed time points after a stroke. The findings indicate that NAGH-treated rats exhibited significant improvements in motor functions and cognitive tests compared to those treated with a vehicle. Additionally, both NAGH and NAD have shown potential in extending the therapeutic window for stroke treatment, significantly reducing neural damage and enhancing behavioral recovery.
Another significant patent involves copper-catalyzed methods for forming carbon-heteroatom and carbon-carbon bonds. This invention outlines a process that utilizes a copper catalyst and various ligands to facilitate the formation of complex chemical structures, which can have wide-ranging applications in organic synthesis.
Career Highlights
Throughout his career, Jon Clarence Antilla has worked with prestigious institutions such as the Massachusetts Institute of Technology and the University of South Florida. His work has not only contributed to academic advancements but has also paved the way for practical applications in medical treatments and chemical processes.
Collaborations
Antilla has collaborated with esteemed colleagues, including Stephen L. Buchwald and Artis Klapars, further enhancing the impact of his research through shared expertise and innovative ideas.
Conclusion
Jon Clarence Antilla's contributions to stroke treatment and chemical bond formation exemplify the spirit of innovation in the scientific community. His patents reflect a commitment to advancing medical science and chemistry, ultimately benefiting society through improved treatment options and methodologies.