John W Whitehead

Title: The Innovations of John W Whitehead

Introduction

John W Whitehead is a notable inventor based in Ware, GB. He has made significant contributions to the field of chemistry, particularly in the preparation of lactam derivatives. His work has implications for the development of compounds with potential therapeutic applications.

Latest Patents

John W Whitehead holds a patent for a process for the preparation of lactam derivatives. This invention relates to a process for creating a compound of formula (I), where R can represent a hydrogen atom or a methyl or ethyl group. The process involves cyclizing a compound of formula (IV), which may optionally be alkylated to produce a compound in which R is methyl or ethyl. The compound of formula (I) serves as an intermediate in the preparation of 2,3,4,5-tetrahydro-2-[(imidazol-4(or 5)-yl)methyl]-1H-pyrido[4,3-b]indol-1-ones, which exhibit 5-HT3 antagonist activity.

Career Highlights

Throughout his career, John W Whitehead has been associated with Glaxo Group Limited, where he has contributed to various research initiatives. His expertise in chemical processes has been instrumental in advancing the company's research objectives.

Collaborations

John has collaborated with notable colleagues, including Keith Mills and Ian H Coates. These partnerships have fostered innovation and have led to advancements in their respective fields.

Conclusion

John W Whitehead's contributions to the field of chemistry, particularly through his patent on lactam derivatives, highlight his role as an influential inventor. His work continues to impact the development of important therapeutic compounds.