Company Filing History:
Years Active: 1999-2002
Title: Innovations in Bladder Disease Treatment by John W. Warren
Introduction
John W. Warren is a notable inventor based in Baltimore, MD (US), recognized for his contributions to the field of bladder disease research. He holds a total of 4 patents that focus on innovative diagnostic and treatment methods for interstitial cystitis (IC), a chronic condition affecting the bladder.
Latest Patents
Warren's latest patents include groundbreaking work on the diagnosis and treatment of interstitial cystitis. One of his significant inventions is a method for diagnosing IC through the use of urine levels of heparin-binding epidermal growth factor-like growth factor (HB-EGF). This discovery highlights the abnormal levels of HB-EGF in the urine of IC patients compared to asymptomatic controls, providing a potential diagnostic marker for the disease.
Additionally, Warren has developed a method for treating interstitial cystitis using recombinant HB-EGF. His research indicates that the administration of HB-EGF can block the effects of an anti-proliferative factor (APF) found in IC urine specimens, thereby promoting epithelial cell proliferation and reducing chronic damage to the bladder epithelium. This innovative approach offers hope for patients suffering from IC and other related conditions.
Career Highlights
John W. Warren is affiliated with the University System of Maryland, where he continues to advance research in bladder health. His work has significantly impacted the understanding and treatment of interstitial cystitis, paving the way for new therapeutic strategies.
Collaborations
Warren has collaborated with esteemed colleagues, including Susan K. Keay and Michael K. Hise, to further enhance the research and development of treatments for bladder diseases.
Conclusion
John W. Warren's innovative patents and research efforts are instrumental in improving the diagnosis and treatment of interstitial cystitis. His work not only contributes to the scientific community but also offers hope to those affected by this challenging condition.