Company Filing History:
Years Active: 1992-1996
Title: Innovations by John W. Shultz
Introduction
John W. Shultz is a notable inventor based in Elkhart, Indiana, recognized for his contributions to the field of enzymatic research. He holds two patents that focus on enhancing the stability of proteases, which are crucial in various industrial applications, particularly in detergents.
Latest Patents
Shultz's latest patents include "Proteases of Altered Stability to Autolytic Degradation" and "Bleach Stable Enzymes." The first patent addresses the susceptibility of proteases to autolytic degradation. The method outlined in this invention identifies susceptible autolysis sites that can be cleaved to produce discrete fragments. By chemically modifying the amino acids at or near these cleavage sites or altering the DNA sequence encoding these amino acids through site-directed mutagenesis, Shultz aims to create autolysis-stable proteases. This invention is particularly beneficial for alkaline proteases, which are produced in large quantities and utilized as detergent additives. The second patent focuses on identifying cleavage sites of enzymes in the presence of hypochlorite, specifically at tryptophan residues. By modifying or deleting tryptophan, the invention seeks to produce more stable enzymes that retain their activity in hypochlorite environments, making them suitable for detergent compositions.
Career Highlights
John W. Shultz is currently associated with Solvay Enzymes, Inc., where he continues to innovate in the field of enzymatic applications. His work has significantly impacted the development of more effective and stable enzymes for industrial use.
Collaborations
Shultz has collaborated with notable colleagues, including George Boguslawski and Josephine Grosch, contributing to advancements in enzymatic research and applications.
Conclusion
John W. Shultz's innovative work in the field of proteases has led to significant advancements in enzyme stability, particularly for applications in detergents. His contributions continue to influence the industry positively.