Company Filing History:
8 out of 403 
3 out of 9 
2 out of 89 
Years Active: 1989-2002
Title: The Innovative Contributions of John W. Lyle
Introduction
John W. Lyle, based in Belmar, NJ, is a notable inventor with a remarkable portfolio consisting of 17 patents. His inventive work primarily focuses on developing compositions for treating neuropathic pain, leveraging the therapeutic potential of anticonvulsants in conjunction with nontoxic substances.
Latest Patents
Among his latest patents are significant advancements in pain management. One of his innovations involves an anticonvulsant-containing composition aimed at treating neuropathic pain. This invention details how the effectiveness of the anticonvulsant gabapentin can be enhanced when combined with a nontoxic antagonist for the N-methyl-D-aspartate receptor. Furthermore, another patent outlines the use of tramadol, where its analgesic effectiveness is significantly potentiated by the administration of a nontoxic NMDA receptor blocker, either prior to or alongside tramadol.
Career Highlights
Throughout his career, John W. Lyle has made substantial contributions to the field of medicinal chemistry. His work has largely been associated with well-respected institutions, notably Virginia Commonwealth University and Algos Pharmaceutical Corporation. His creativity and expertise have pushed the boundaries of therapeutic approaches in pain management.
Collaborations
John has worked alongside esteemed colleagues such as David J. Mayer and Donald D. Price. Their collaborative efforts have contributed to the development of innovative solutions for complex health issues, showcasing the strength of teamwork in the pursuit of scientific advancements.
Conclusion
John W. Lyle's contributions to medical innovation exemplify the impact of inventive thought processes on modern health treatments. With a growing portfolio of patents and a dedicated career focused on improving patient outcomes, Lyle continues to be a relevant figure in the field of pharmacology and pain management. His innovative approaches are sure to influence future research and development in these critical areas of healthcare.