Location History:
- Tucson, AZ (US) (1997)
- Westfield, NJ (US) (1998 - 2002)
- Lansdale, PA (US) (1999 - 2007)
Company Filing History:
9 out of 4,770 
1 out of 1 
2 out of 832,718 Years Active: 1997-2007
Title: John W Hess: Innovator in Genetic Research
Introduction
John W Hess is a notable inventor based in Lansdale, PA (US), recognized for his contributions to genetic research and biotechnology. With a total of 12 patents, Hess has made significant strides in understanding the genetic factors associated with various diseases, particularly type 1 diabetes.
Latest Patents
Hess's latest patents include a method of screening for modulators of LRP5 activity. This invention introduces a novel receptor, LDL-receptor-related protein-5 (LRP-5), along with its encoding nucleic acid. The gene is linked to type 1 diabetes, specifically the IDDM susceptibility gene IDDM4. The invention encompasses nucleic acids, coding sequences, oligonucleotide primers and probes, polypeptides, and pharmaceutical compositions. It also outlines methods for diagnosis, prognosis, and treatment of diseases related to this gene, including autoimmune diseases, viral infections, and conditions like Alzheimer's disease and osteoporosis.
Another significant patent involves the LDL-receptor, which presents a novel receptor, LDL-receptor related protein-3 (LRP-3). Similar to his previous work, this invention also focuses on the gene's association with type 1 diabetes and provides various methods for treatment and diagnosis of related diseases.
Career Highlights
Throughout his career, John W Hess has worked with prominent companies, including Merck & Company, Inc. His experience in the pharmaceutical industry has greatly influenced his research and patent developments.
Collaborations
Hess has collaborated with notable colleagues such as Joseph A Borkowski and Michael S Phillips, contributing to advancements in genetic research and biotechnology.
Conclusion
John W Hess stands out as an influential inventor in the field of genetic research, with a focus on diseases like type 1 diabetes. His innovative patents and collaborations have paved the way for new diagnostic and therapeutic methods, showcasing the importance of genetic research in modern medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.