This inventor holds 1 USPTO granted patent. Top assignee: Harvard College. Active years: 2015.
Company Filing History:
Years Active: 2015
Title: John W Hanna: Innovator in Proteasome Activity Enhancement
Introduction
John W Hanna is a notable inventor based in Boston, MA (US). He has made significant contributions to the field of biochemistry, particularly in enhancing proteasome activity within cells. His innovative work has implications for understanding protein degradation processes, which are crucial for cellular function.
Latest Patents
John W Hanna holds a patent for "Methods and compositions for enhancing proteasome activity." This invention relates to methods and compositions that enhance the activity of the proteasome in a cell by modulating the activity of Ubp6 (in yeast) or Usp14 (in humans), which are endogenous inhibitors of the proteasome. The methods and compositions can partially or completely reduce the inhibitory activity of Usp14 on the proteasome, thereby specifically enhancing its protein-degradation activity. Additionally, the invention provides methods for screening to identify inhibitors of Ubp6, Usp14, or both.
Career Highlights
John W Hanna is affiliated with Harvard College, where he continues to engage in research and innovation. His work has garnered attention for its potential applications in various biological and medical fields.
Collaborations
Some of his notable coworkers include Daniel J Finley and Nathaniel A Hathaway, who have collaborated with him on various research projects.
Conclusion
John W Hanna's contributions to enhancing proteasome activity represent a significant advancement in biochemistry. His innovative methods and compositions have the potential to impact the understanding of protein degradation in cells.