Location History:
- Tampa, FL (US) (1997)
- Cold Spring Arbor, NY (US) (2011)
- Cold Spring Harbor, NY (US) (2002 - 2017)
Company Filing History:
12 out of 15 
4 out of 1,933 
1 out of 1 Years Active: 1997-2017
Title: Innovations in Vaccine Immunotherapy by John W. Hadden
Introduction
John W. Hadden is a prominent inventor based in Cold Spring Harbor, NY, with a remarkable portfolio of 17 patents. His work primarily focuses on vaccine immunotherapy, particularly in treating cancers in immune-suppressed patients. Hadden's innovative approaches aim to enhance T-cell immunity and improve treatment outcomes for patients facing significant health challenges.
Latest Patents
Hadden's latest patents include groundbreaking methods for vaccine immunotherapy targeting lymphoma and cervical cancer in immune-suppressed patients. One of his notable inventions involves a method for overcoming mild to moderate immune suppression by inducing the production of naive T-cells and restoring T-cell immunity. This method also includes exposing these naive T-cells to endogenous or exogenous antigens at appropriate sites. Additionally, he has developed a method for unblocking immunization at a regional lymph node, which promotes the differentiation and maturation of immature dendritic cells. This process allows for the presentation of processed peptides by mature dendritic cells, ultimately exposing tumor peptides to T-cells to enhance immunization. Furthermore, Hadden's work includes a method for treating cancer and other persistent lesions by administering an effective amount of a natural cytokine mixture as an adjuvant to the administered antigen.
Career Highlights
Throughout his career, Hadden has made significant contributions to the field of immunotherapy. He has worked with notable organizations such as Irx Therapeutics, Inc. and the University of South Florida, where he has furthered his research and development efforts in vaccine technology. His innovative work has positioned him as a leader in the field of cancer treatment.
Collaborations
Hadden has collaborated with esteemed colleagues, including James E. Egan and Kathy L. Signorelli, to advance his research and develop effective therapeutic strategies. These collaborations have played a crucial role in enhancing the impact of his inventions.
Conclusion
John W. Hadden's contributions to vaccine immunotherapy represent a significant advancement in the treatment of cancers in immune-suppressed patients. His innovative methods and dedication to research continue to inspire progress in the medical field.