John W Gotto

Title: Innovations of John W. Gotto in Vaccine Development

Introduction

John W. Gotto is a notable inventor based in Suffern, NY (US), recognized for his significant contributions to the field of vaccine development. With a total of nine patents to his name, Gotto has made strides in creating efficacious vaccines aimed at preventing diseases caused by Bordetella pertussis.

Latest Patents

One of Gotto's latest patents focuses on a vaccine designed to prevent disease caused by Bordetella pertussis. This innovative vaccine comprises pertussis antigens, including filamentous hemagglutinin, detoxified lymphocytosis promoting factor, and a 69 kilodalton outer membrane protein. The unique aspect of this invention is that the antigens are individually purified before being combined to form the vaccine. Furthermore, the invention allows for the combination of these antigens in various ratios, including those not achievable in whole cell or co-purified acellular pertussis vaccines. The pertussis antigens can also be combined with other individually purified pertussis antigens, structural components, adjuvants, stabilizers, and non-pertussis vaccine components.

Career Highlights

Gotto's career is marked by his work at the American Cyanamid Company, where he has been instrumental in advancing vaccine technology. His dedication to research and innovation has led to the development of vaccines that enhance public health and safety.

Collaborations

Throughout his career, Gotto has collaborated with esteemed colleagues, including Kiran M. Khandke and Ursula Eul. These partnerships have contributed to the successful development of his patented inventions.

Conclusion

John W. Gotto's work in vaccine development exemplifies the impact of innovation in healthcare. His contributions continue to play a vital role in the prevention of infectious diseases, showcasing the importance of research and collaboration in the field of medicine.