This inventor holds 5 USPTO granted patents and 3 published patent applications and 1 EPO patent. Top assignees: Case Western Reserve University, The Cleveland Clinic Foundation. Active years: 2007-2018.
Location History:
- Chagrin Falls, OH (US) (2007 - 2012)
- Cleveland, OH (US) (2018)
Company Filing History:
5 out of 1,363 
5 out of 1,071 
Years Active: 2007-2018
Title: Innovations of John W. Crabb
Introduction
John W. Crabb is a notable inventor based in Chagrin Falls, Ohio. He has made significant contributions to the field of biomedical research, particularly in the development of antibodies and methods for treating age-related conditions. With a total of 5 patents, his work has had a meaningful impact on medical science.
Latest Patents
Among his latest patents is the invention of an isolated anti-carboxyethylpyrrole (anti-CEP) antibody or antigen binding portion thereof. This invention includes a heavy chain variable domain with three CDRs that have at least 90% sequence identity to specific sequences. Another significant patent involves methods of reducing angiogenesis related to age-related macular degeneration (AMD) or choroidal neovascularization. This method comprises administering an agent that inhibits one or more CEP protein adducts, effectively reducing angiogenesis in individuals.
Career Highlights
John W. Crabb has worked with prestigious institutions such as the Cleveland Clinic Foundation and Case Western Reserve University. His career has been marked by a commitment to advancing medical research and developing innovative solutions for complex health issues.
Collaborations
Throughout his career, Crabb has collaborated with esteemed colleagues, including Robert G. Salomon and Xiaorong Gu. These partnerships have contributed to the success of his research and the development of his patents.
Conclusion
John W. Crabb's contributions to the field of biomedical research through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in medical treatments and therapies.