Company Filing History:
1 out of 1,586 
1 out of 832,891 Years Active: 2008-2013
Title: John-Stephen Taylor: Innovator in Cancer Diagnosis and Therapy
Introduction
John-Stephen Taylor is a notable inventor based in St. Louis, MO (US). He has made significant contributions to the field of cancer diagnosis and therapy through his innovative patents. With a total of 2 patents, Taylor's work focuses on developing advanced methods for targeting cancer-specific nucleic acid sequences.
Latest Patents
One of Taylor's latest patents is titled "Cell permeable nanoconjugates of shell-crosslinked knedel (SCK) and peptide nucleic acids ('PNAs') with uniquely expressed or over-expressed mRNA targeting sequences for early diagnosis and therapy of cancer." This invention describes a functional biologically active particle conjugate that is useful for diagnosing and treating cancer. It comprises a nanoscale particle associated with an intracellular targeting ligand, which includes a PNA or another nuclease-resistant oligonucleotide analog. This ligand binds selectively to uniquely expressed or overexpressed mRNA specific to cancer or disease states in living mammals. Notably, the unr mRNA can be targeted by the antisense sequence PNA50.
Another significant patent by Taylor is "Nucleic acid triggered catalytic drug and probe release." This invention provides methods and combinations of compositions for modulating diseases caused by a subject possessing a disease-specific nucleic acid sequence. The methods include treatment, prevention, and inhibition of diseases by administering a combination of a prodrug component, drug, and catalytic component, allowing for the catalytic release of the drug upon contact with the disease-specific nucleic acid sequence.
Career Highlights
Throughout his career, John-Stephen Taylor has worked with various institutions, including Washington University. His research has focused on innovative solutions for cancer treatment, showcasing his commitment to advancing medical science.
Collaborations
Taylor has collaborated with notable colleagues such as Matthew L Becker and Huafeng Fang. These collaborations have contributed to the development of his groundbreaking patents and research.
Conclusion
John-Stephen Taylor's contributions to cancer diagnosis and therapy through his innovative patents highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in medical technology and treatment options.