John R Ogez

Title: The Innovations of John R. Ogez

Introduction

John R. Ogez is a notable inventor based in Redwood City, CA (US). He has made significant contributions to the field of biotechnology, particularly in the isolation of polypeptides. With a total of 7 patents to his name, Ogez has established himself as a key figure in his industry.

Latest Patents

One of his latest patents is titled "Aqueous multiple-phase isolation of polypeptide." This method describes a process for isolating an exogenous polypeptide in a non-native conformation from cells, such as an aqueous fermentation broth. The process involves contacting the polypeptide with a chaotropic agent and a reducing agent, along with phase-forming species to create multiple aqueous phases. One of these phases is enriched in the polypeptide while being depleted of biomass solids and nucleic acids from the cells. The method ideally results in two aqueous phases, with the upper phase being enriched in the polypeptide.

Career Highlights

John R. Ogez works at Genentech, Inc., a leading biotechnology company known for its innovative approaches to drug development. His work has been instrumental in advancing techniques for protein isolation, which are crucial for various applications in medicine and research.

Collaborations

Ogez has collaborated with several esteemed colleagues, including Stuart E. Builder and David Reifsnyder. These collaborations have further enhanced the impact of his work in the field.

Conclusion

John R. Ogez's contributions to biotechnology through his innovative patents and collaborations highlight his importance as an inventor. His work continues to influence the methods used in polypeptide isolation, showcasing the significance of his research in the industry.