John P Long

Title: The Innovations of John P Long

Introduction

John P Long is a notable inventor based in Iowa City, IA (US). He has made significant contributions to the field of pharmacology, particularly with his innovative compounds that serve as potential therapeutic agents. With a total of 4 patents, Long's work has implications for treating various medical conditions.

Latest Patents

One of Long's latest patents is for S-11-hydroxy-10-methylaporphine and its biologically active salt forms. These compounds act as 5-HT.sub.1A inhibitors, which can be utilized as antidotes for the effects of cocaine and as appetite suppressants. The chemical formula for S-11 Hydroxy-10-Methylaporphine is represented as: ##STR1##. Another significant patent involves a method of increasing renal blood flow using dopamine derivatives. Certain N,N-dialkyl substituted derivatives of dopamine (DA) have been shown to enhance renal blood flow without impacting cardiac contractility. Notably effective derivatives include N,N-di-n-propyl DA and N-n-propyl-N-n-butyl DA, among others.

Career Highlights

Throughout his career, John P Long has been associated with reputable institutions such as the University of Iowa Research Foundation and University Patents, Inc. His work has not only advanced scientific understanding but has also paved the way for practical applications in medicine.

Collaborations

Long has collaborated with esteemed colleagues, including Joseph G Cannon and John N Diana. These partnerships have contributed to the development and refinement of his innovative ideas.

Conclusion

John P Long's contributions to the field of pharmacology through his patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of therapeutic agents that address critical health issues.