Company Filing History:
Years Active: 2004-2007
Title: Innovations and Contributions of John P. Carulli
Introduction
John P. Carulli is a notable inventor based in Southboro, MA (US). He has made significant contributions to the field of genetics, particularly in the area of bone development. With a total of 4 patents, his work has implications for diagnosing and treating conditions such as osteoporosis.
Latest Patents
One of his latest patents is focused on the high bone mass gene of 11q13.3. This invention relates to methods and materials used to isolate and detect a high bone mass gene and its corresponding wild-type gene, along with mutants thereof. The genes identified in this invention are implicated in bone development. The invention also provides nucleic acids, including coding sequences, oligonucleotide primers and probes, proteins, cloning vectors, expression vectors, transformed hosts, methods of developing pharmaceutical compositions, and methods of identifying molecules involved in bone development. In preferred embodiments, this invention is directed to methods for treating, diagnosing, and preventing osteoporosis. Another significant patent involves isolated nucleic acids comprising novel genes of a 20 cM region of human chromosome 11q13.3 and the proteins encoded by these genes. This patent includes expression vectors and host cells containing these genes or fragments thereof, as well as antibodies to the proteins encoded by these nucleic acids.
Career Highlights
Throughout his career, John P. Carulli has worked with various organizations, including Genome Therapeutics Corporation. His innovative work has contributed to advancements in genetic research and therapeutic applications.
Collaborations
John has collaborated with notable individuals in his field, including Randall D. Little and Robert R. Recker. These collaborations have further enhanced the impact of his inventions and research.
Conclusion
John P. Carulli's contributions to genetics and bone development through his patents demonstrate his commitment to advancing medical science. His work continues to influence the field and offers potential solutions for critical health issues.