Company Filing History:
Years Active: 2025
Title: Innovations of John Nolin in Botulinum Toxin Purification
Introduction
John Nolin is an accomplished inventor based in Storvreta, Sweden. He has made significant contributions to the field of biotechnology, particularly in the purification of botulinum toxin. His innovative methods have the potential to enhance the safety and efficacy of botulinum toxin applications.
Latest Patents
John Nolin holds a patent for a method of purifying botulinum toxin. This technology relates to commercial-scale methods for purifying botulinum toxin compositions obtained from cell cultures. The purification methods are based on a series of filtration and chromatographic separation steps that produce a high-purity botulinum toxin composition. This composition comprises botulinum toxin protein molecules (approximately 150 kDa) in solution, which is free, essentially free, or substantially free of botulinum toxin complexes and animal products. Notably, the method does not involve precipitation, lyophilization, or centrifugation steps, allowing for the production of highly pure, highly active, free botulinum toxin protein molecules in solution.
Career Highlights
John Nolin is associated with Galderma Holding SA, a company known for its focus on dermatological products and treatments. His work at Galderma has allowed him to apply his innovative purification methods in a practical setting, contributing to advancements in the field.
Collaborations
John has collaborated with notable colleagues, including Ulf Stahl and Peter Frank. These collaborations have likely enriched his research and development efforts, fostering a productive environment for innovation.
Conclusion
John Nolin's contributions to the purification of botulinum toxin represent a significant advancement in biotechnology. His innovative methods promise to improve the quality and safety of botulinum toxin applications in various fields.