Los Angeles, CA, United States of America

John M Timmerman

USPTO Granted Patents = 4 

Average Co-Inventor Count = 2.2

ph-index = 2

Forward Citations = 10(Granted Patents)


Company Filing History:


Years Active: 2013-2025

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4 patents (USPTO):Explore Patents

Title: Innovations of John M Timmerman in Cancer Treatment

Introduction

John M Timmerman is a prominent inventor based in Los Angeles, CA, who has made significant contributions to the field of cancer treatment through his innovative patents. With a total of four patents to his name, Timmerman focuses on enhancing adoptive T cell therapies, which are crucial in the fight against cancer.

Latest Patents

One of Timmerman's latest patents involves the development of antibody-interferon fusion proteins aimed at boosting the cancer-fighting capacity of adoptive T cell therapies. This method utilizes antibody-interferon (Ab-IFN) fusion proteins to enhance the effectiveness of T cells that are manipulated and grown outside the body before being reintroduced to the patient. The goal is to enable these infused T cells to target and destroy tumors through an immunologic attack. Notable adoptive T cell therapies mentioned include chimeric antigen receptor (CAR) T cells, tumor-infiltrating lymphocytes (TILs), virus-specific T cells, and T cell receptor transgenic T cells.

Another significant patent focuses on anti-CSPG4 fusions with interferon for the treatment of malignancy. This patent describes chimeric constructs that demonstrate considerable efficacy against various cancers. These constructs consist of a targeting moiety that specifically binds to CSPG4, which is attached to an interferon or a mutant interferon. The constructs may include anti-CSPG4 antibodies linked to different types of interferons, such as interferon alpha, beta, or gamma.

Career Highlights

Timmerman is affiliated with the University of California, where he continues to advance his research and innovations in cancer therapies. His work has garnered attention for its potential to significantly improve treatment outcomes for cancer patients.

Collaborations

Some of Timmerman's notable collaborators include Sherie L Morrison and Kham M Trinh, who contribute to the research and development of his innovative therapies.

Conclusion

John M Timmerman's contributions to cancer treatment through his innovative patents highlight the importance of research and development in the medical field. His work continues to pave the way for advancements in adoptive T cell therapies, offering hope for improved cancer treatment options.

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