This inventor holds 2 USPTO granted patents. Top assignee: The University of Texas System. Active years: 2004-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2004-2011
Title: Innovations of John M Dietschy in Cholesterol Metabolism
Introduction
John M Dietschy is a prominent inventor based in Dallas, TX (US), known for his significant contributions to the field of cholesterol metabolism. With a total of 2 patents, his work focuses on developing methods and compositions that aim to reduce cholesterolemia and its associated effects.
Latest Patents
Dietschy's latest patents include innovative compositions and methods for modulating cholesterol metabolism. These inventions are directed towards screening compounds that affect cholesterol levels, particularly in terms of absorption and bile acid synthesis. The patents describe the use of transgenic cells and animals that lack one or both alleles of the LXRα gene. Therapeutic methods are also provided, which are designed to reduce cholesterol levels in suitable subjects. The reduction can be achieved by decreasing cholesterol absorption, increasing bile acid synthesis, or through a combination of both methods. RXR agonists, such as rexinoid compounds, are highlighted as particularly useful in decreasing cholesterol absorption. Additionally, the patents discuss candidate compounds that modulate the expression of ABC-1 in cells expressing RXR, along with methods for identifying and creating modulators of ABC-1.
Career Highlights
John M Dietschy is affiliated with the University of Texas System, where he continues to advance research in cholesterol metabolism. His work has had a significant impact on understanding and treating cholesterol-related health issues.
Collaborations
Dietschy has collaborated with notable colleagues, including David John Mangelsdorf and Joyce J Repa, contributing to the advancement of research in his field.
Conclusion
John M Dietschy's innovative work in cholesterol metabolism has led to valuable patents that provide insights into reducing cholesterol levels and improving health outcomes. His contributions continue to influence research and therapeutic approaches in this critical area of health.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile