John Kehoe

Title: The Innovations of John Kehoe

Introduction

John Kehoe is an accomplished inventor based in Saint Davids, PA (US). He has made significant contributions to the field of biotechnology, particularly in the development of antibodies that can detect and isolate tyrosine-sulfated polypeptides. With a total of 2 patents, his work has implications for various immunological assays.

Latest Patents

Kehoe's latest patents include innovations related to anti-sulfotyrosine antibodies. These antibodies are designed to specifically detect and isolate polypeptides that are tyrosine-sulfated. The technology allows for the discrimination between non-sulfated and sulfated forms of proteins through various immunological assays, such as ELISAs, immunoblots, and Western Blots. Utilizing a phage-display system, he generated single chain antibodies (scFvs) that specifically recognize sulfotyrosine-containing peptides. This work has led to the creation of full-length, sulfotyrosine-specific immunoglobulins.

Career Highlights

John Kehoe is currently employed at Los Alamos National Security, LLC, where he continues to advance his research in antibody development. His innovative work has positioned him as a notable figure in the biotechnology sector.

Collaborations

Throughout his career, Kehoe has collaborated with esteemed colleagues, including Carolyn Ruth Bertozzi and Andrew M Bradbury. These partnerships have further enriched his research and contributed to the advancement of his inventions.

Conclusion

John Kehoe's contributions to the field of biotechnology through his patents on anti-sulfotyrosine antibodies demonstrate his commitment to innovation and scientific advancement. His work continues to have a significant impact on immunological research and applications.