Location History:
- New Haven, CT (US) (2010)
- Cornwall on Hudson, NY (US) (2012 - 2013)
Company Filing History:
Years Active: 2010-2013
Title: Innovations of John K Wickiser in Riboswitch Technology
Introduction
John K Wickiser is a notable inventor based in Cornwall on Hudson, NY (US). He has made significant contributions to the field of genetic engineering, particularly through his work on riboswitches. With a total of three patents to his name, Wickiser's innovations have the potential to revolutionize gene therapy and metabolic engineering.
Latest Patents
Wickiser's latest patents focus on riboswitches, methods for their use, and compositions for use with riboswitches. His research has revealed that certain natural mRNAs function as metabolite-sensitive genetic switches, which directly bind small organic molecules. This binding alters the conformation of the mRNA, leading to changes in gene expression through various mechanisms. Modified versions of these natural riboswitches can serve as designer genetic switches, controlled by specific effector compounds known as trigger molecules. These natural switches are promising targets for antibiotics and other small molecule therapies. Furthermore, the architecture of riboswitches allows for the construction of new non-immunogenic genetic control elements, enabling innovative applications in living biosensors, metabolic engineering, and advanced gene therapy treatments.
Career Highlights
Wickiser's career is marked by his dedication to advancing the understanding and application of riboswitch technology. His work has not only contributed to academic knowledge but also holds practical implications for therapeutic interventions.
Collaborations
Wickiser has collaborated with esteemed colleagues such as Ronald R Breaker and Ali Nahvi, further enhancing the impact of his research in the scientific community.
Conclusion
John K Wickiser's innovative work on riboswitches exemplifies the intersection of genetic engineering and therapeutic development. His contributions are paving the way for new approaches in gene therapy and metabolic engineering, showcasing the potential of riboswitch technology in modern science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.